Volume : 3, Issue : 3, JUN 2019

The Innovations in Tablet Coating: A Review

Kajal Pundir, Dr. Bharat Parashar

Abstract

Solid dosage forms are coated for a number of reasons, the most important of which is controlling the release profiles and bioavailability of the active ingredient. The amount of coating on the surface of a tablet is critical to the effectiveness of the oral dosage form. Tablets are usually coated in horizontal rotating pans with the coating solution sprayed onto the free surface of the tablet bed. The advantages of tablet coating are taste masking, odour masking, physical and chemical protection, protects the drug from the gastric environment etc. In these latest technologies coating materials are directly coated on to the surface of solid dosage forms without using any solvent various solvent less coatings are available such as electrostatic dry coating, magnetically assisted impaction coating, compression coating, powder coating and fluid bed coating, supercell coating. Magnetically assisted impaction coating, electrostatic dry coating, coating and Supercell coating technology also are available latest technique of coating. Using the Discrete Element Method (DEM), tablet coating can be simulated on the computer. ICH guidelines also prefer the avoidance of organic solvents in pharmaceutical dosage formulations considering products safety profile. This review discusses the basic concepts of tablet coating, the recent advancements made, the problem faced during the process, their solutions and coating evaluation.

Keywords

Tablet coating, Magnetically assisted Impaction coating, Supercell coating, Discrete element method.

Article : Download PDF

Cite This Article

Article No : 6

Number of Downloads : 0

References

  1. Lachman L., Lieberman, H. A., Joseph L. K. The Theory and Practice of Industrial Pharmacy; Varghese Publishing House; Mumbai; Third Edition; Pp .297-321.

 

  1. Lachman L., Liberman H., and Kanig J. The Theory and Practice of Industrial Pharmacy; Third Edition: 293-345, 346-373.

 

  1. Aulton M. Pharmaceutics: The Science of Dosage Form Design; International Student Edition: 304-321, 347-668.

 

  1. Remington’s The Science and Practice of Pharmacy. Volume-I. 21st ed. Indian Edition, Lippincot Williams and Wilkins. 2005: 929-938.

 

  1. Kamble N. et al. Innovations in tablet coating technology: A review. International Journal of Applied Biology and Pharmaceutical Technology. 2011; 214-218.

 

  1. Remington‘s The Science and Practice of Pharmacy. Volume-I. 21st ed. Indian Edition, Lippincot Williams and Wilkins. 2005; 929-938.

 

  1. Cole G, Hogan J, Aulton M. Pharmaceutical Coating Technology. Taylor and Francis, London, 1995; 1-5.

 

  1. Qiao M. et al A Novel Electrostatic Dry Powder Coating Process for Pharmaceutical Dosage Forms: Immediate Release Coatings for Tablets. European J Pharm Biopharm. 2010: 304-310.

 

  1. Pawar A. et al Advances in Pharmaceutical Coatings. International Journal of ChemTech Research. 2010: 733-737.

 

  1. Mazumder M, Sims R, Biris A. Twenty-first century research needs in electrostatic processes applied to research needs in electrostatic processes applied to industry and medicine. Chem Eng Sci. 2006; 61: 2192-2211.

 

  1. Hogan, John E, Page, Trevor R, Linda S, John N. Powder coating composition for electrostatic coating of pharmaceutical substrates. US Patent 6, 406, 738. 2002 June 18.

 

  1. Ramlakhan, Chang Yu Wu, Satoru Watano, Rajesh N. Dave, Robert Pfeffer, Dry particle coating using magnetically assisted impaction coating: modification of surface properties and optimization of system and operating parameters. Powder Technol. 2000; 112(1-2): 137-148.

 

  1. Mazumder M, Sims R, Biris A. Twenty-first century research needs in electrostatic processes applied to research needs in electrostatic processes applied to industry and medicine. Chem Eng Sci. 2006; 61: 2192-2211.

 

  1. Remington J. Remington: The Science and Practice of Pharmacy; Nineteenth Edition: Volume II 1615-1641.

 

  1. American Pharmaceutical Reviews; 2001; 4(3): 28-35.

 

  1. Vyas S., Khar R. Controlled Drug Delivery Concepts and Advances; First Edition: 219-256.

 

  1. https://scholar.google.com/scholar?rlz=1C1_____enIN838IN838&um=1&ie=UTF-8&lr&cites=7256284450029155024

 

  1. Porter SC, Felton LA. Techniques to assess film coatings and evaluate film-coated products. Drug Development and Industrial Pharmacy 2010; 36: 128–42.

 

  1. Pawar A et al. Advances in Pharmaceutical Coatings. International Journal of Chem. Tech Research 2010; 5: 733-737.

 

  1. Srivastava S, Mishra G. Fluid Bed Technology: Overview and Parameters for Process Selection. International Journal of Pharmaceutical Sciences and Drug Research 2010; 2(4): 236-246.